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3D Visualization

Three-dimensional representation of the effects of a stimulating electrode around a bundle of nerve fibers. Caption: Image of neuron stimulation model with electric field lines and gradient.
4 Files
33.26 KB
No Records
MIT
Ignacio Pascual updated on August 15, 2019
simcore, osparc, electrical stimulation +2 More
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Mapping of ICN Neurons in a 3D Reconstructed Rat Heart

The distribution of neurons in the intrinsic cardiac nervous system (ICN) were mapped and visualized in a 3D reconstruction of a male rat heart.
9 Files
55.71 GB
No Records
CC-BY-4.0
Clara Leung updated on August 14, 2019
heart, anatomy, 3d reconstructed heart +3 More
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Multi-scale human cardiac electrophysiology models

A computational workflow for integration and implementation of a reusable and reproducible human cardiac multi-scale electrophysiology model. Caption: Illustration of ion channels and action potential propogation in cardiac tissue
4 Files
127.1 KB
No Records
MIT
Ignacio Pascual updated on August 14, 2019
osparc, simcore, cardiac electrophysiology +2 More
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Multi-scale rabbit cardiac electrophysiology models

A computational workflow for integration and implementation of a reusable and reproducible rabbit cardiac multi-scale electrophysiology model. Caption: Illustration of ion channels and action potential propogation in cardiac tissue
4 Files
124.53 KB
No Records
MIT
Manuel Guidon updated on August 14, 2019
simcore, osparc, computational workflows +2 More
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Small Enteric Neural Network Simulator

This network is designed to study the interactions of different types of synaptic potentials in a realistic enteric neuron and the effects of varying the voltage-dependent ion channels in the output neuron membrane. Caption: Simulated neuron voltage
4 Files
25.07 KB
No Records
MIT
Ignacio Pascual updated on August 5, 2019
osparc, simcore, network simulator +5 More
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CLARITY and three-dimensional (3D) imaging of the mouse and porcine colonic innervation

Regional ENS 3D structure/phenotype, axonal projections and connectivity in the mouse and pig colon.
25 Files
35.44 MB
28 Records
CC-BY-4.0
Pu-Qing Yuan updated on July 31, 2019
obsolete peritreme, large intestine, electron microscope +6 More
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Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

iDISCO-cleared mouse hearts with PGP9.5 staining for neural structures.
41 Files
7.22 GB
34 Records
CC-BY-4.0
Pradeep Rajendran updated on July 31, 2019
mus musculus, adult organism, immunolabeling +7 More
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Cardioneural Recordings

Methodology of neural recordings using array electrodes. How to analyze for signal to noise, spike sorting and higher level analysis.
45 Files
1.64 GB
32 Records
CC-BY-4.0
Leonardo Guercio updated on July 31, 2019
myocardium of atrium, heart, nodose ganglion +3 More
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Spatial distribution and morphometric characterization of vagal afferents associated with the myenteric plexus of the rat stomach

Spatial distribution and morphometric characterization of vagal afferents (specifically: intraganglionic laminar endings (IGLEs)) associated with the myenteric plexus of the rat stomach.
269 Files
538.38 MB
84 Records
CC-BY-4.0
Bartek Rajwa updated on July 31, 2019
stomach, vagal, afferent +9 More
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Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat

Influence of left vagal stimulus pulse parameters on vagal and gastric activity in rat.​
119 Files
41.26 MB
51 Records
CC-BY-4.0
Bartek Rajwa updated on July 31, 2019
vagus nerve stimulation, vns, gastric electrical stimulation +7 More
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Spatial distribution and morphometric characterization of vagal afferents (intramuscular arrays (IMAs)) within the longitudinal and circular muscle layers of the rat stomach

Spatial distribution and morphometric characterization of vagal afferents (specifically: intramuscular arrays (IMAs)) within the longitudinal and circular muscle layers of the rat stomach.
389 Files
1.08 GB
156 Records
CC-BY-4.0
Bartek Rajwa updated on July 31, 2019
stomach, vagal, afferent +8 More
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Distribution of Nitregic Cholinergic and all MP Neurons

Contains source data and reconstructed images of nNOS, cholinergic and glial distribution in the murine large intestine.
66 Files
147.09 GB
2 Records
CC-BY-4.0
Dante Heredia updated on July 31, 2019
large intestine, neuron distribution, murine enteric nervous system +1 More
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Molecular Phenotype Distribution of Single Rat ICN Neurons

Intracardiac neuron (ICN) samples were collected from a female rat heart using laser capture microdissection. We acquired transcriptomics data for 154 genes from the 151 samples we collected. Images of sampled neurons allow for 3D reconstruction of data.
2156 Files
48.5 GB
202 Records
CC-BY-4.0
Alison Moss updated on July 31, 2019
rattus norvegicus, sprague dawley, heart +7 More
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Immunocytochemistry Pig Heart ICN

Pig ICN Confocal Immunocytochemistry. Yucatan Pigs fixed and RAGP region excised sectioned. Stained with Ab to determine morphology, phenotype present. Compare and contrast to other ICN supportive of functional data.
24 Files
550.92 MB
9 Records
CC-BY-4.0
Gabrielle Pine updated on July 31, 2019
ragp, heart, immunocytochemistry +3 More
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Influence of direct colon tissue electrical stimulation on colonic motility in anesthetized male Yucatan minipig

Direct proximal colon, transverse colon and colorectum wall electrical stimulation; monitor colon wall bio-impedance and colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.
171 Files
64.04 GB
192 Records
CC-BY-4.0
Muriel Larauche updated on July 31, 2019
large intestine, sense organ, sus scrofa +7 More
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High resolution manometry

Organ bath studies of motility recorded from entire sections surgically excised human colon.
84 Files
379.84 MB
50 Records
CC-BY-4.0
Phil Dinning updated on July 31, 2019
colon, manometry, neurogenic +2 More
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Anatomical Model Viewer

Render different human tissue types in three dimensions with the option to highlight or segment parts of: musculature, vasculature, nerve tissue, viscera and skeletal structure. Caption: Screenshot of anatomical viewer with subject Jeduk
4 Files
31.39 KB
No Records
MIT
Ignacio Pascual updated on July 31, 2019
osparc, simcore, anatomy +4 More
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2D Plot

Interactive example for plotting gene expression using the RAW Graphs platform. Data are obtained from Prof. Leah Reznikov at University of Florida. Caption: Plot created using O2S2PARC platform with RAW Graphs
4 Files
64.28 KB
No Records
MIT
Ignacio Pascual updated on July 31, 2019
osparc, simcore, raw graphs
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SPARC Nerve Activity Predictor (SNAP)

Interactive, AI-informed computational model of stimulus parameter-dependent vagal nerve responses resulting from bipolar, constant-current stimuli. Caption: Simulation of compound action potential propagation
4 Files
25.17 KB
No Records
MIT
Ignacio Pascual updated on July 31, 2019
simcore, osparc, vagus nerve +4 More
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opencor-py model

Computes the cardiac myocyte action potential for the sympathetic drive input setting on the MAP-Core portal. Caption: Illustration of a whole body flatmap (centre) and central nervous system map (left) with a neural pathway highlighted.
4 Files
81.81 KB
No Records
MIT
Ignacio Pascual updated on July 31, 2019
osparc, simcore, pacemaker +2 More
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Quantification of rat gastric enteroendocrine cells

Enteroendocrine cells (EEC) are cells found in the gut that secrete hormones. This data describes EECs within the rat stomach, including their hormone content, shapes, positions within the mucosa, relationship to other cells and regional distribution.
430 Files
27.87 GB
64 Records
CC-BY-4.0
Martin Stebbing updated on July 31, 2019
enteroendocrine cells, gastrointestinal hormones, ghrelin +15 More
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Functional Recordings from Pig ICN

Pig monitored for ICN recoding with cardiovascular output monitoring, Cervical vagi stimulation
21 Files
1.08 GB
3 Records
CC-BY-4.0
Erin Bailey updated on July 31, 2019
heart
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Functional neuronal nodose recording from pig - Cardiac field chemical and mechanical stimulation

Recordings made form pig nodose ganglion with linear bipolar electrodes. Cardiac stimulation of various files via mechanical-touch- and chemical to determine response type- unipolar or multimodal from neurons residing within nodose ganglion.
20 Files
522.8 MB
10 Records
CC-BY-4.0
Erin Bailey updated on July 31, 2019
heart
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Vagus nerve stimulation promotes gastric emptying by increasing pyloric opening measured with magnetic resonance imaging

Vagus nerve stimulation promotes gastric emptying by increasing pyloric opening measured with magnetic resonance imaging.
118 Files
7.55 GB
53 Records
CC-BY-4.0
Bartek Rajwa updated on July 31, 2019
pyloric sphincter, holtzman sprague-dawley rat, alimentary part of gastrointestinal system +4 More
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A multi-scale model of cardiac electrophysiology

We develop a workflow containing differential equation models of cardiac physiology that automate the execution of simulations with user defined options of outputs from a single cell, 1 or 2-Dimensional tissue, and a pseudo-ECG output.
172 Files
8.08 MB
8 Records
CC-BY-4.0
Parya Aghasafari updated on July 31, 2019
heart
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Morris_DEMO_OT2OD023854_BrainstemNeuronRecording_2019

One complete single experiment data set for the 2019 ISAN meeting
28 Files
213.91 GB
30 Records
CC-BY-4.0
Kendall Morris updated on July 31, 2019
lung, felis catus, electron microscope +10 More
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Distribution and coexpression patterns of specific cell markers of enteroendocrine cells in pig gastric epithelium

In monogastric animals, the stomach can be divided into different functional regions. This dataset describes regional differences in wall structure and in the types and densities of hormone secreting cells in the pig stomach.
423 Files
43.27 GB
50 Records
CC-BY-4.0
Martin Stebbing updated on July 31, 2019
stomach, gut hormones, ghrelin +16 More
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Quantification of the relationship between rat gastric nerve fibers and enteroendocrine cells (EEC)

Enteroendocrine cells (EECs) in the stomach are thought to modulate the desire to eat via nerves that send signals from the gut to the brain. In this dataset we examine the structural relationship between nerve endings and EECs in the rat gastric mucosa.
277 Files
282.19 GB
39 Records
CC-BY-4.0
Martin Stebbing updated on July 31, 2019
enteroendocrine cells, ghrelin, 5-hydroxytryptamine +15 More
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Rat vagus nerve morphology

Micrographs of cross sections of cervical and abdominal rat vagus nerve stained with Masson's trichrome.
107 Files
3.74 GB
67 Records
CC-BY-4.0
Nikki Pelot updated on July 31, 2019
neural anatomy, vagus nerve morphology, autonomic nervous system +6 More
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Intracranial EEG Epilepsy - Study 6

Data for a patient with epilepsy obtained for clinical treatment and collected for research, consisting of a large intracranial EEG dataset (strip electrodes) with multiple seizures.
138 Files
34.88 GB
23 Records
CC-0-1.0
Jenaye Johnson updated on July 31, 2019
epilepsy, eeg, intracranial +2 More