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Public Datasets

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Quantified Morphology of the Rat Vagus Nerve

Binary traces from segmentation of cross sections of cervical and subdiaphragmatic rat vagus nerves stained with Masson's trichrome. Quantified effective nerve diameter, effective fascicle diameter, number of fascicles, and perineurium thickness.
144 Files
205.92 MB
40 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Nicole Pelot updated on September 22, 2020
rattus norvegicus, vagus nerve stimulation, vagus nerve morphology + More
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Excitation Properties of Computational Models of Unmyelinated Peripheral Axons

Data and plotting code for excitation responses of multiple single compartment and multi-compartment models of peripheral unmyelinated axons
1,999 Files
962.77 MB
6 Records
CC-BY-4.0
Nicole Pelot updated on September 22, 2020
unmyelinated axon, voltage-gated ion channels, vagus nerve + More
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Comparison of the Intrinsic Cardiac Nervous System Across Male and Female Rat Hearts

Single neurons were mapped and cardiac anatomy was annotated in image volumes of male and female rat hearts to compare the intrinsic cardiac nervous system between individuals and across sexes.
77 Files
439.79 GB
37 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Clara Leung updated on September 17, 2020
rat intrinsic cardiac neurons, knife edge scanning microscopy, 3d heart reconstructions + More
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Anatomy and Histology of the Domestic Pig in the Context of Vagus Nerve Stimulation

Incorporation of Motor Efferent Branches of Vagus into VNS Activation
2,700 Files
232.07 GB
943 Records
CC-BY-4.0
Kip Ludwig updated on September 8, 2020
vagotopy, electroceuticals, vagus nerve stimulation + More
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Neurofauna Rat

This detailed anatomical representation of a rat that can be viewed and explored in a 3D viewer.
6 Files
39.74 KB
No Records
MIT
Ignacio Pascual updated on August 27, 2020
rat, pns, heart + More
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Human Islet Microvasculature Analysis

Human pancreas cleared with passive CLARITY, immunostained, and imaged on a Zeiss 710 microscope. Image analysis of islet and islet collagen IV volumes were determined using Vesselucida360.
128 Files
30.13 GB
53 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Martha Campbell-Thompson updated on August 24, 2020
pancreas, confocal image, microvasculature + More
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Characterizing the effect of feeding distension and emetic stimuli on gastric myoelectric activity in ferrets

This dataset contains gastric myoelectric activity recorded from multi-electrode arrays, surgically implanted on the serosal surface of the GI tract to study perturbations due to mechanical or chemical stimuli in acute and chronic preparations of ferrets
20,315 Files
364.42 GB
20,354 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Charles Horn updated on August 24, 2020
nausea, ferret, electrogastrogram + More
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Mapping of ICN Neurons in a 3D Reconstructed Rat Heart

Single intrinsic cardiac nervous system (ICN) neurons were marked in an image volume of heart sections that was anatomically delineated for the 3D reconstruction of the whole heart with mapped locations of individual ICN neurons.
23 Files
55.71 GB
19 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Clara Leung updated on August 4, 2020
rattus norvegicus, knife edge scanning microscopy, rodent cardiac anatomy + More
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Rat Vagus Nerve Stained with Masson's Trichrome

Micrographs of cross sections of cervical and abdominal rat vagus nerve stained with Masson's trichrome.
163 Files
2.76 GB
52 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Nicole Pelot updated on August 4, 2020
vagus nerve stimulation, rattus norvegicus, autonomic nervous system + More
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Quantified Morphology of the Human Vagus Nerve with Anti-Claudin-1

Immunohistochemistry micrographs of human vagus nerves labeled with anti-claudin-1. Binary traces from segmentation to quantify effective nerve diameter, effective fascicle diameter, number of fascicles, and perineurium thickness.
386 Files
2.76 GB
47 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Nicole Pelot updated on August 4, 2020
vagus nerve stimulation, autonomic nervous system, vagus nerve morphology + More
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Human Vagus Nerve Stained with Masson's Trichrome

Micrographs of cross sections of cervical and abdominal human vagus nerve stained with Masson's trichrome.
167 Files
8.95 GB
113 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Nicole Pelot updated on July 17, 2020
vagus nerve stimulation, autonomic nervous system, vagus nerve morphology + More
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Generic mouse colon scaffold

Annotated mouse colon scaffold available for registration of segmented neural anatomical-functional mapping of enteric neural circuits.
28 Files
3.85 MB
4 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Mabelle Lin updated on July 17, 2020
mesenteric zone, colon, mouse
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Pig Vagus Nerve Stained with Masson's Trichrome

Micrographs of cross sections of cervical and abdominal pig vagus nerve stained with Masson's trichrome.
160 Files
5.04 GB
70 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Nicole Pelot updated on July 16, 2020
vagus nerve stimulation, autonomic nervous system, vagus nerve morphology + More
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Compound action potential integrated use case example

An example dataset of a vagus nerve compound action potential for use in demonstrating the integration between the various components of the SPARC DRC. This dataset is only intended for use in demonstrations.
9 Files
129.2 KB
2 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

David Nickerson updated on June 3, 2020
vagus nerve
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Real-time particle-by-particle detection of erythrocyte camouflaged microsensor with extended circulation time in the bloodstream

Raw data of sensor response measured in vitro (plate reader, flow cytometer, DiFC) and in vivo (DiFC)
410 Files
7.76 GB
No Records
CC-BY-4.0
Isen Andrew Calderon updated on May 29, 2020
optode sensor, in vivo flow cytometer, sodium sensing + More
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Kember Cardiac Nerve Model

Simulation and viewer for a model of autonomic control of cardiac function contributed by Prof. Guy Kember from Dalhousie University. Caption: A schematic of the mathematical model for closed-loop, networked cardiac regulation
6 Files
62.93 KB
No Records
MIT
Katie Zhuang updated on May 28, 2020
heart, myocardial infarction, autonomic
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Functional recordings from the pig intrinsic cardiac nervous system (ICN)

Pigs monitored for ICN recoding via cardiovascular output monitoring after cervical vagi stimulation.
26 Files
1.08 GB
21 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Jeffrey Ardell updated on May 19, 2020
sus scrofa domesticus, cardiac icn, vagus + More
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High resolution manometry

Organ bath studies of motility recorded from entire sections surgically excised human colon.
95 Files
400.62 MB
95 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Phil Dinning updated on May 19, 2020
homo sapiens, neurogenic, manometry + More
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Phrenic Nerve Immunohistochemistry

Immunohistochemistry of phrenic nerve afferents in acute intermittent hypoxia and hemisection injury conditioned rats
33,574 Files
310.6 GB
1 Record
CC-BY-4.0

Sponsored by

NIH SPARC Program

Gordon Mitchell updated on May 18, 2020
sparc
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Lower urinary track nerve responses to high-density epidural spinal cord stimulation ML-RNEL 4908 Bladder SCS

This dataset contains recordings of compound nerve action potentials from the pelvic and pudendal nerves and its various branches in response to electrical stimulation on the epidural surface of the sacral spinal cord in anesthetized cats.
42,405 Files
925.41 GB
33 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Max Novelli updated on May 9, 2020
spinal cord stimulation, pelvic nerve, electrical stimulation + More
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Submandibular ganglion stained by bungarotoxin and nanosensors in mouse

This data set describes staining of submandibular ganglion with a-bungarotoxin (BTX) and nanosensor developed by the Clark lab. BTX staining is used as a gold standard to validate the localization of nanosensor.
53 Files
206.67 MB
25 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Heather Clark updated on May 19, 2020
submandibular ganglion, bungarotoxin, acetylcholine receptor + More
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Electrophysiology in dog after subcutaneous nerve stimulation

Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs
6,882 Files
298.31 GB
47 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Peng-Sheng Chen updated on May 9, 2020
autonomic nervous system, neuromodulation, arrhythmias + More
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iBAT Sympathetic Innervation Circuit Pseudorabies Viral Tracing in reporter mice

Utilizes pseudorabies virus (PRV) retrograde tracing in combination w/reporter mice, iDISCO, & confocal/light-sheet microscopy to identify the location of pre- & post-ganglionic neurons and nerves that selectively innervate the iBAT in the mouse.
208 Files
780.29 GB
48 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Heike Muenzberg updated on May 19, 2020
tissue clearing, pseudorabies virus, idisco + More
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Using Chamber Pressure Pump

These files are a description on how to build and program a high precision pressure pump to control tissue distension in Ussing chambers. In addition there is a video clip to show the ramp tissues distension
29 Files
29.75 MB
13 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Michael Schemann updated on May 9, 2020
microcontroller, syringe pump, instrumentation
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Cardioneural Recordings

Methodology of neural recordings using array electrodes. How to analyze for signal to noise, spike sorting, and higher-level analysis.
59 Files
1.64 GB
47 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

scott john updated on May 9, 2020
microarray, nodose ganglion, cardiac + More
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